About: Albuterol Sulfate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Albuterol Sulfate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Albuterol Sulfate
NSC_Code
  • 289928
UMLS_CUI
  • C0543495
CAS_Registry
  • 51022-70-9
FDA_UNII_Code
  • 021SEF3731
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 41339
PDQ_Closed_Trial_Search_ID
  • 41339
Chemical_Formula
  • 2C13H21NO3.H2O4S
Legacy_Concept_Name
  • Albuterol_Sulfate
CHEBI_ID
  • CHEBI:2550
FULL_SYN
  • Albuterol SulfatePTNCI
  • ALBUTEROL SULFATEPTFDA021SEF3731
  • Salbutamol SulphateSYNCI
  • VentolinBRNCI
  • ProventilBRNCI
DEFINITION
  • The sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.NCI
code
  • C47957
sameAs
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