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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Valsartan
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Valsartan
UMLS_CUI
  • C0216784
CAS_Registry
  • 137862-53-4
FDA_UNII_Code
  • 80M03YXJ7I
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 464172
PDQ_Closed_Trial_Search_ID
  • 464172
Chemical_Formula
  • C24H29N5O3
Legacy_Concept_Name
  • Valsartan
CHEBI_ID
  • CHEBI:9927
FULL_SYN
  • ValsartanPTDCP32063
  • N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valineSNNCI
  • VALSARTANPTFDA80M03YXJ7I
  • DiovanBRNCI
  • CGP 48933CNNCI
  • ValsartanPTNCI
  • L-Valine, N-(1-oxopentyl)-N-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-SNNCI
DEFINITION
  • An orally active nonpeptide triazole-derived antagonist of angiotensin (AT) II with antihypertensive properties. Valsartan selectively and competitively blocks the binding of angiotensin II to the AT1 subtype receptor in vascular smooth muscle and the adrenal gland, preventing AT II-mediated vasoconstriction, aldosterone synthesis and secretion, and renal reabsorption of sodium, and resulting in vasodilation, increased excretion of sodium and water, a reduction in plasma volume, and a reduction in blood pressure.NCI
code
  • C47781
sameAs
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