About: Tubocurarine Chloride     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Tubocurarine Chloride
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Tubocurarine Chloride
NSC_Code
  • 36387
UMLS_CUI
  • C0282372
CAS_Registry
  • 6989-98-6
FDA_UNII_Code
  • 900961Z8VR
Contributing_Source
  • FDA
Chemical_Formula
  • C37H41N2O6.Cl.HCl.5H2O
Legacy_Concept_Name
  • Tubocurarine_Chloride
FULL_SYN
  • TUBOCURARINE CHLORIDEPTFDA900961Z8VR
  • 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido(3',2':14,15)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinoliniumSNNCI
  • 2,3,13a,14,15,16,25,25a-Octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-, Chloride, Hydrochloride,(13aR,25aS)-SNNCI
  • Tubocuraranium, 7',12'-Dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyl-, Chloride, HydrochlorideSNNCI
  • AmerizolSYNCI
  • Tubocurarine ChloridePTNCI
  • TubocurareBRNCI
DEFINITION
  • The chloride salt form of tubocurarine, a naturally occurring curare alkaloid isolated from the bark and stem of Chondodendron tomentosum with a muscle relaxant property. Tubocurarine chloride competes with acetylcholine for the nicotinic receptors at the neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine and blocking the neural transmission without depolarizing the postsynaptic membrane. This may lead to skeletal muscle relaxation and paralysis.NCI
code
  • C47777
sameAs
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