About: Trihexyphenidyl Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Trihexyphenidyl Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Trihexyphenidyl Hydrochloride
UMLS_CUI
  • C0591114
CAS_Registry
  • 52-49-3
FDA_UNII_Code
  • AO61G82577
Contributing_Source
  • FDA
Chemical_Formula
  • C20H31NO.HCl
Legacy_Concept_Name
  • Trihexyphenidyl_Hydrochloride
FULL_SYN
  • TRIHEXYPHENIDYL HYDROCHLORIDEPTFDAAO61G82577
  • ArtaneBRNCI
  • Trihexyphenidyl HydrochloridePTNCI
  • 1-Piperidinepropanol, alpha-cyclohexyl-alpha-phenyl-, HydrochlorideSNNCI
  • CyclodolSYNCI
DEFINITION
  • The hydrochloride salt form of trihexyphenidyl, a synthetic, substituted piperidine with parasympatholytic activity used mostly in Parkinson's disease. Trihexyphenidyl hydrochloride antagonizes activities of acetylcholine via muscarinic receptors. This balances the cholinergic and dopaminergic activity in the basal ganglia leading to an improvement of classic Parkinson symptoms such as rigidity and tremor. In addition, trihexyphenidyl hydrochloride exerts a direct antispasmodic effect on smooth muscle.NCI
code
  • C47771
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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