About: Trazodone Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Trazodone Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Trazodone Hydrochloride
NSC_Code
  • 292811
UMLS_CUI
  • C0701914
CAS_Registry
  • 25332-39-2
FDA_UNII_Code
  • 6E8ZO8LRNM
Contributing_Source
  • FDA
Chemical_Formula
  • C19H22ClN5O.HCl
Legacy_Concept_Name
  • Trazodone_Hydrochloride
CHEBI_ID
  • CHEBI:9655
FULL_SYN
  • Trazodone HydrochloridePTNCI
  • 1,2,4-Triazolo(4,3-a)pyridin-3(2H)-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-, MonohydrochlorideSNNCI
  • TRAZODONE HYDROCHLORIDEPTFDA6E8ZO8LRNM
  • 2-(3-(4-(3-Chlorophenyl)piperazin-1-y)propyl)-1,2,4-triazolo(4,3-a)pyridine-3(2H)-one HydrochlorideSNNCI
  • DesyrelBRNCI
  • TrialodineBRNCI
DEFINITION
  • The hydrochloride salt form of trazodone, a synthetic triazolopyridine derivative with antidepressant and sedative properties. Based on studies from animal models, trazodone selectively inhibits the re-uptake of serotonin by synaptosomes in the brain, thereby increasing serotonin levels in the synaptic cleft and potentiating serotonin activity. Trazodone is not a monoamine oxidase inhibitor and, unlike amphetamine-type drugs, does not stimulate the central nervous system. The sedative effect of trazodone is likely via alpha-adrenergic and mild histamine H1 blocking actions.NCI
code
  • C47767
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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