About: Sulfisoxazole     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Sulfisoxazole
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Sulfisoxazole
NSC_Code
  • 13120
  • 33807
  • 38588
UMLS_CUI
  • C0038745
CAS_Registry
  • 127-69-5
FDA_UNII_Code
  • 740T4C525W
Contributing_Source
  • FDA
Chemical_Formula
  • C11H13N3O3S
Legacy_Concept_Name
  • Sulfisoxazole
CHEBI_ID
  • CHEBI:102484
FULL_SYN
  • SULFISOXAZOLEPTFDA740T4C525W
  • SulfisoxazolePTNCI
  • 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamideSNNCI
DEFINITION
  • A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfisoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.NCI
code
  • C47740
sameAs
http://linked.open...y/mesh/hasConcept
is sameAs of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 32 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software