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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Sulfanilamide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Sulfanilamide
NSC_Code
  • 7618
UMLS_CUI
  • C0038702
CAS_Registry
  • 63-74-1
FDA_UNII_Code
  • 21240MF57M
Contributing_Source
  • FDA
Chemical_Formula
  • C6H8N2O2S
Legacy_Concept_Name
  • Sulfanilamide
CHEBI_ID
  • CHEBI:45373
FULL_SYN
  • SULFANILAMIDEPTFDA21240MF57M
  • SulfanilamidePTNCI
  • 4-AminobenzenesulfonamideSNNCI
  • AVCBRNCI
  • TrysulBRNCI
  • 4-SulfamoylanilineSNNCI
  • SultrinBRNCI
DEFINITION
  • An organic sulfur compound structurally similar to p-aminobenzoic acid (PABA) with antibacterial property. Sulfanilamide competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.NCI
code
  • C47738
sameAs
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