About: Sertaconazole Nitrate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Sertaconazole Nitrate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Sertaconazole Nitrate
UMLS_CUI
  • C1528751
CAS_Registry
  • 99592-39-9
FDA_UNII_Code
  • 1DV05410M5
Contributing_Source
  • FDA
Chemical_Formula
  • C20H15Cl3N2OS.HNO3
Legacy_Concept_Name
  • Sertaconazole_Nitrate
FULL_SYN
  • SERTACONAZOLE NITRATEPTFDA1DV05410M5
  • 1H-Imidazole, 1-(2-((7-chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-, MononitrateSNNCI
  • ZalainSYNCI
  • ErtaczoBRNCI
  • DermofixSYNCI
  • Sertaconazole NitratePTNCI
DEFINITION
  • The nitrate salt form of sertaconazole, a synthetic imidazole derivative with antifungal property. Sertaconazole nitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols and the inhibition of ergosterol synthesis, an essential component of the cell membrane of fungi. This leads to a disruption of cell membrane permeability and leakage of adenine triphosphate (ATP) and other constituents from fugal cells.NCI
code
  • C47716
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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