About: Pyrithione Zinc     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Pyrithione Zinc
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pyrithione Zinc
NSC_Code
  • 290409
UMLS_CUI
  • C0078792
CAS_Registry
  • 13463-41-7
  • 3590-23-6
FDA_UNII_Code
  • R953O2RHZ5
Contributing_Source
  • FDA
Chemical_Formula
  • 2C5H4NOS.Zn
Legacy_Concept_Name
  • Pyrithione_Zinc
CHEBI_ID
  • CHEBI:32076
FULL_SYN
  • Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-SNNCI
  • 2-Mercaptopyridine 1-oxide Zinc SaltSYNCI
  • PYRITHIONE ZINCPTFDAR953O2RHZ5
  • Zinc PyrithioneSYNCI
  • Pyrithione ZincPTNCI
  • Zinc, bis(2-pyridylthio)-, N,N'-dioxideSNNCI
  • Zinc Pyridine-2-thiol 1-oxideSYNCI
  • Bis(1-hydroxy-2(1H)-pyridinethionato)zincSYNCI
DEFINITION
  • A coordination complex of the zinc ion and pyrithione, a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects. Although the exact mechanism of action remains to be fully elucidated, pyrithione zinc appears to interfere with the membrane transport of ions and metabolites, ultimately leading to a loss of metabolic control. In addition, this agent causes an influx of copper, leading to a reduction in the activity of iron-sulphur proteins resulting in growth inhibition.NCI
code
  • C47698
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