About: Promazine Hydrochloride

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Promazine Hydrochloride
rdfs:subClassOf	ANTIPSYCHOTICS Phenothiazines
Has_Free_Acid_Or_Base_Form	PROMAZINE
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Promazine Hydrochloride
NSC_Code	17468
UMLS_CUI	C0546875
CAS_Registry	53-60-1
FDA_UNII_Code	U16EOR79U4
Contributing_Source	FDA
Chemical_Formula	C17H20N2S.HCl
Legacy_Concept_Name	Promazine_Hydrochloride
CHEBI_ID	CHEBI:8460
FULL_SYN	Promazine HydrochloridePTNCI PROMAZINE HYDROCHLORIDEPTFDAU16EOR79U4 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, MonohydrochlorideSNNCI TalofenSYNCI SparineSYNCI 10-(3-(Dimethylamino)propyl)phenothiazine MonohydrochlorideSNNCI StarazinSYNCI
DEFINITION	The hydrochloride salt form of promazine, a phenothiazine derivative with antipsychotic and antiemetic properties. Promazine hydrochloride blocks postsynaptic dopamine receptors D1 and D2 in the mesolimbic and medullary chemoreceptor trigger zone (CTZ), thereby decreasing stimulation of the vomiting center in the brain and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks alpha-adrenergic receptors and exhibits strong anticholinergic activity.NCI
code	C47691
sameAs	PROMAZINE HYDROCHLORIDE
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0017698
is Has_Salt_Form of	PROMAZINE
is sameAs of	PROMAZINE HYDROCHLORIDE PROMAZINE HYDROCHLORIDE

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