About: Pemoline     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Pemoline
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pemoline
NSC_Code
  • 169499
  • 25159
UMLS_CUI
  • C0030800
CAS_Registry
  • 2152-34-3
FDA_UNII_Code
  • 7GAQ2332NK
Contributing_Source
  • FDA
Chemical_Formula
  • C9H8N2O2
Legacy_Concept_Name
  • Pemoline
FULL_SYN
  • 4(5H)-Oxazolone, 2-amino-5-phenyl-SNNCI
  • PEMOLINEPTFDA7GAQ2332NK
  • CylertBRNCI
  • 2-Imino-4-keto-5-phenyltetrahydrooxazoleSNNCI
  • PemolinePTNCI
  • 5-PhenylisohydantionSYNCI
DEFINITION
  • An oxazolidine compound with central nervous system (CNS) stimulant property. Although pemoline has pharmacological activity similar to other CNS stimulants, the exact mechanism and site of action are unknown. This agent has minimal sympathomimetic properties, but animal studies indicate it may work through dopaminergic mechanisms. Pemoline has been withdrawn from the U.S. market because of the agent's association with life threatening hepatic failure.NCI
code
  • C47655
sameAs
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