About: Nalbuphine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Nalbuphine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Nalbuphine Hydrochloride
UMLS_CUI
  • C0600099
CAS_Registry
  • 23277-43-2
FDA_UNII_Code
  • ZU4275277R
Contributing_Source
  • FDA
Chemical_Formula
  • C21H27NO4.HCl
Legacy_Concept_Name
  • Nalbuphine_Hydrochloride
CHEBI_ID
  • CHEBI:7455
FULL_SYN
  • N-Cyclobutylmethyl-14-hydroxydihydronormorphine HydrochlorideSNNCI
  • Nalbuphine HydrochloridePTNCI
  • NALBUPHINE HYDROCHLORIDEPTFDAZU4275277R
  • (5alpha,6alpha)-17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol HydrochlorideSNNCI
  • NubainBRNCI
DEFINITION
  • The hydrochloride salt form of nalbuphine, a synthetic phenanthrene opioid with opiate agonist and antagonist effects, used to treat moderate to severe pain and provide preoperative and postoperative analgesia and sedation. Nalbuphine hydrochloride binds to kappa-, mu- and delta-opioid receptors but not to sigma-opioid receptors. This opioid exerts its analgesic actions primarily through kappa-opioid-receptor agonism and partially through mu-opioid receptor agonism.NCI
code
  • C47629
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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