About: Methenamine Hippurate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Methenamine Hippurate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Methenamine Hippurate
UMLS_CUI
  • C0066105
CAS_Registry
  • 5714-73-8
FDA_UNII_Code
  • M329791L57
Contributing_Source
  • FDA
Chemical_Formula
  • C9H9NO3.C6H12N4
Legacy_Concept_Name
  • Methenamine_Hippurate
FULL_SYN
  • Hexamethylene Tetramine HippurateSYNCI
  • METHENAMINE HIPPURATEPTFDAM329791L57
  • UrexBRNCI
  • ViaptaSYNCI
  • Glycine, N-benzoyl, compound with 1,3,5,7-tetraazatricyclo(3.3.1.1(sup 3,7))decane(1:1)SNNCI
  • Methenamine HippuratePTNCI
  • HippramineSYNCI
DEFINITION
  • The hippurate salt form of methenamine, a prodrug and inactive weak base that slowly hydrolyzes in acidic urine to ammonia and the effective, urinary tract antiseptic formaldehyde. Formaldehyde probably exerts its antibacterial effect by denaturation of protein. Depending on the urinary concentrations, formaldehyde is either bactericidal or bacteriostatic. Formaldehyde urinary concentrations are dependent on urine pH, volume, and flow rate. Formaldehyde acts as an antibacterial agent against gram-positive and gram-negative organisms.NCI
code
  • C47610
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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