About: Erythromycin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Erythromycin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Carbohydrate
Preferred_Name
  • Erythromycin
NSC_Code
  • 55929
UMLS_CUI
  • C0014806
CAS_Registry
  • 114-07-8
FDA_UNII_Code
  • 63937KV33D
Contributing_Source
  • FDA
ALT_DEFINITION
  • A bacteriostatic antibiotic substance produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 39234
PDQ_Closed_Trial_Search_ID
  • 39234
Chemical_Formula
  • C37H67NO13
Legacy_Concept_Name
  • Erythromycin
CHEBI_ID
  • CHEBI:42355
FULL_SYN
  • ERYTHROMYCINPTFDA63937KV33D
  • ERYTHROMYCINSYDTPNSC0055929
  • ErycSYDTPNSC0055929
  • ErythromycinPTNCI
  • ERYCBRNCI
  • ErydermSYDTPNSC0055929
  • ErythromycinPTDCP02930
  • RP-MycinSYDTPNSC0009161
  • E-MycinBRNCI
  • Ery-TabBRNCI
  • EryDermBRNCI
  • RP-MycinBRNCI
  • IlotycinBRNCI
  • RobimycinBRNCI
DEFINITION
  • A broad-spectrum, macrolide antibiotic with antibacterial activity. Erythromycin diffuses through the bacterial cell membrane and reversibly binds to the 50S subunit of the bacterial ribosome. This prevents bacterial protein synthesis. Erythromycin may be bacteriostatic or bactericidal in action, depending on the concentration of the drug at the site of infection and the susceptibility of the organism involved.NCI
code
  • C476
sameAs
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