About: Mebendazole     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Mebendazole
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Mebendazole
NSC_Code
  • 184849
UMLS_CUI
  • C0025023
CAS_Registry
  • 31431-39-7
FDA_UNII_Code
  • 81G6I5V05I
Contributing_Source
  • FDA
Chemical_Formula
  • C16H13N3O3
Legacy_Concept_Name
  • Mebendazole
CHEBI_ID
  • CHEBI:6704
FULL_SYN
  • Methyl 5-benzoyl benzimidazole-2-carbamateSNNCI
  • MebendazolePTNCI
  • VermoxBRNCI
  • R 17635CNNCI
  • (5-Benzoyl-1H-benzimidazol-2-yl)-carbamic Acid Methyl EsterSNNCI
  • MEBENDAZOLEPTFDA81G6I5V05I
DEFINITION
  • A synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake. This results in a depletion of glycogen stores and leads to reduced formation of ATP required for survival and reproduction of the helminth. This eventually causes the helminths death.NCI
code
  • C47595
sameAs
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