About: Levonordefrin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Levonordefrin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Levonordefrin
UMLS_CUI
  • C0520472
CAS_Registry
  • 18829-78-2
  • 829-74-3
FDA_UNII_Code
  • V008L6478D
Contributing_Source
  • FDA
Chemical_Formula
  • C9H13NO3
Legacy_Concept_Name
  • Levonordefrin
FULL_SYN
  • LEVONORDEFRINPTFDAV008L6478D
  • Neo-CobefrinSYNCI
  • LevonordefrinPTNCI
  • 1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)-,(R-(R*,S*))-SNNCI
  • (-)-alpha-(1-Aminoethyl)-3,4-dihydroxybenzyl AlcoholSNNCI
DEFINITION
  • The levoisomer of nordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects. Levonordefrin's antihypertensive effect is exerted through activation of alpha 2-adrenergic receptors in the cardiovascular control center of the CNS thereby suppressing the sympathetic output from the brain and subsequently lowering blood pressure. Levonordefrin binds to and activates peripheral alpha 2- adrenergic receptors, thereby causing vasoconstriction.NCI
code
  • C47584
sameAs
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