About: Insulin Glargine

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Insulin Glargine
rdfs:subClassOf	Therapeutic Insulin
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Insulin Glargine
UMLS_CUI	C0907402
CAS_Registry	160337-95-1
FDA_UNII_Code	2ZM8CX04RZ
Contributing_Source	FDA
ALT_DEFINITION	A drug used to control the amount of sugar in the blood of patients with diabetes. It is a form of the hormone insulin that is made in the laboratory. Insulin glargine controls blood sugar longer than insulin does. It is a type of therapeutic insulin.NCI-GLOSS
PDQ_Open_Trial_Search_ID	561310
PDQ_Closed_Trial_Search_ID	561310
Chemical_Formula	C267H404N72O78S6
Legacy_Concept_Name	Insulin_Glargine_Recombinant
FULL_SYN	INSULIN GLARGINEPTFDA2ZM8CX04RZ Insulin GlarginePTNCI LantusPTNCI-GLOSSCDR0000658820 Insulin Glargine RecombinantSYNCI LantusBRNCI insulin glargine recombinantPTNCI-GLOSSCDR0000658818 insulin glarginePTNCI-GLOSSCDR0000658817
DEFINITION	A recombinant human insulin analog with long-acting, blood glucose-lowering activity. Insulin glargine, like regular types of human insulin, regulates glucose metabolism by binding to insulin receptors on muscle and fat cells, thereby facilitating the cellular uptake of glucose. This lowers blood glucose levels. At the same time, insulin glargine inhibits the liver's conversion of stored glycogen into glucose, which also contributes to lower blood glucose levels. Insulin glargine also inhibits lipolysis in adipose tissue, inhibits proteolysis, and enhances protein synthesis. (NCI05)NCI
code	C47564
sameAs	INSULIN,GLARGINE,HUMAN/rDNA INSULIN,GLARGINE,HUMAN/rDNA
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0361589
is sameAs of	INSULIN,GLARGINE,HUMAN/rDNA INSULIN,GLARGINE,HUMAN/rDNA INSULIN,GLARGINE,HUMAN/rDNA

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