About: Guanfacine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Guanfacine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Guanfacine Hydrochloride
UMLS_CUI
  • C0700472
CAS_Registry
  • 29110-48-3
FDA_UNII_Code
  • PML56A160O
Contributing_Source
  • FDA
Chemical_Formula
  • C9H9Cl2N3O.HCl
Legacy_Concept_Name
  • Guanfacine_Hydrochloride
FULL_SYN
  • Guanfacine HydrochloridePTNCI
  • N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide HydrochlorideSNNCI
  • GUANFACINE HYDROCHLORIDEPTFDAPML56A160O
  • TenexBRNCI
  • EstulicSYNCI
DEFINITION
  • The hydrochloride salt form of guanfacine, a centrally acting alpha-2 adrenergic agonist with antihypertensive activity. Alpha-2 receptor stimulation by guanfacine hydrochloride results in a decreased sympathetic outflow from the vasomotor center to the heart, kidneys, and peripheral vasculature. This leads to a decrease in heart rate and peripheral vascular resistance. (NCI05)NCI
code
  • C47550
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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