About: Frovatriptan Succinate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Frovatriptan Succinate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Frovatriptan Succinate
UMLS_CUI
  • C1099777
CAS_Registry
  • 158930-17-7
FDA_UNII_Code
  • D28J6W18HY
Contributing_Source
  • FDA
Chemical_Formula
  • C14H17N3O.C4H6O4.H2O
Legacy_Concept_Name
  • Frovatriptan_Succinate
FULL_SYN
  • 1H-Carbazole-6-carboxamide, 2,3,4,9-tetrahydro-3-(methylamino)-,(3R)-, Butanedioate(1:1)SNNCI
  • Frovatriptan SuccinatePTNCI
  • FROVATRIPTAN SUCCINATEPTFDAD28J6W18HY
  • FrovaBRNCI
DEFINITION
  • The succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity. Frovatriptan succinate binds selectively and with high affinity to 5-HT 1B and presynaptic 5-HT 1D receptors in the extracerebral and intracranial arteries. This leads to an inhibition of serotonin activity and results in vasoconstriction of the painfully dilated blood vessels during migraine attack. Frovatriptan succinate is indicated for the acute treatment of migraine. (NCI05)NCI
code
  • C47544
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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