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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Estazolam
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Estazolam
NSC_Code
  • 290818
UMLS_CUI
  • C0014892
CAS_Registry
  • 29975-16-4
FDA_UNII_Code
  • 36S3EQV54C
Contributing_Source
  • FDA
Chemical_Formula
  • C16H11ClN4
Legacy_Concept_Name
  • Estazolam
CHEBI_ID
  • CHEBI:4858
FULL_SYN
  • 8-Chloro-6-phenyl-4H-(1,2,4)triazolo-(4,3-a)(1,4)benzodiazepineSNNCI
  • ESTAZOLAMPTFDA36S3EQV54C
  • ProSomBRNCI
  • EsilganSYNCI
  • EstazolamPTNCI
DEFINITION
  • A triazolo-benzodiazepine with anxiolytic, anticonvulsant, hypnotic, and muscle relaxant properties. Estazolam binds to the gamma-aminobutyric acid (GABA) receptor at a site distinct from the inhibitory neurotransmitter GABA binding site in the limbic system of the central nervous system (CNS). This binding leads to an opening of the chloride channels, which allows the flow of chloride ions into the neuron, hyperpolarizes the neuronal membrane, inhibits neuronal firing, and leads to a decrease in neuronal excitability.NCI
code
  • C47520
sameAs
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