About: Epinastine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Epinastine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Epinastine Hydrochloride
UMLS_CUI
  • C1321612
CAS_Registry
  • 108929-04-0
FDA_UNII_Code
  • GFM415S5XL
Contributing_Source
  • FDA
Chemical_Formula
  • C16H15N3.HCl
Legacy_Concept_Name
  • Epinastine_Hydrochloride
CHEBI_ID
  • CHEBI:51037
FULL_SYN
  • Epinastine HydrochloridePTNCI
  • EPINASTINE HYDROCHLORIDEPTFDAGFM415S5XL
  • AlesionSYNCI
  • ElestatSYNCI
  • 9,13b-Dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepin-3-amine HydrochlorideSNNCI
DEFINITION
  • An histamine H1 receptor antagonist without sedative activity. Epinastine hydrochloride blocks the histamine H1 receptor and inhibits the release of histamine from mast cells. This prevents the typical allergic symptoms that are caused by histamine activity on capillaries, skin, mucous membranes, and on gastrointestinal and bronchial smooth muscles. Typical histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Epinastine also has affinity for the histamine H2, 5-HT2, and the alpha-1, alpha-2 adrenergic receptors.NCI
code
  • C47512
sameAs
is Has_Salt_Form of
is sameAs of
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