About: Dihydroergotamine Mesylate

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Dihydroergotamine Mesylate
rdfs:subClassOf	NON-OPIOID ANALGESICS Dopamine Agonist
Has_Free_Acid_Or_Base_Form	DIHYDROERGOTAMINE
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Dihydroergotamine Mesylate
UMLS_CUI	C0700532
CAS_Registry	6190-39-2
FDA_UNII_Code	81AXN7R2QT
Contributing_Source	FDA
Chemical_Formula	C33H37N5O5.CH4O3S
Legacy_Concept_Name	Dihydroergotamine_Mesylate
CHEBI_ID	CHEBI:59756
FULL_SYN	Ergotoman-3',6',18-trione,9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-,(5'alpha)-, monomethanesulfonate(salt)SNNCI Dihydroergotamine MesylatePTNCI DIHYDROERGOTAMINE MESYLATEPTFDA81AXN7R2QT MigranalBRNCI 9,10-Dihydroergotamine MesylateSYNCI
DEFINITION	An ergot derivative with agonistic activity for alpha-adrenergic, serotonergic, and dopaminergic receptors. Dihydroergotamine mesylate most likely relieves migraine headaches by binding to and stimulating the 5-HT1D receptor subtype, thereby causing constriction of cerebral blood vessels. However, it has also been proposed that dihydroergotamine mesylate acts upon 5-HT1D receptors on sensory nerve endings of the trigeminal system, thereby decreasing the release of pro-inflammatory neuropeptide release.NCI
code	C47491
sameAs	DIHYDROERGOTAMINE MESYLATE DIHYDROERGOTAMINE MESYLATE
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0330548
is Has_Salt_Form of	DIHYDROERGOTAMINE
is sameAs of	DIHYDROERGOTAMINE MESYLATE DIHYDROERGOTAMINE MESYLATE DIHYDROERGOTAMINE MESYLATE

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