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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Desogestrel
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Desogestrel
UMLS_CUI
  • C0057558
CAS_Registry
  • 54024-22-5
FDA_UNII_Code
  • 81K9V7M3A3
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 743774
PDQ_Closed_Trial_Search_ID
  • 743774
Chemical_Formula
  • C22H30O
Legacy_Concept_Name
  • Desogestrel
CHEBI_ID
  • CHEBI:4453
FULL_SYN
  • DesogestrelPTNCI
  • 13-Ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-olSNNCI
  • DESOGESTRELPTFDA81K9V7M3A3
  • CerazetteBRNCI
DEFINITION
  • A synthetic progestogen structurally related to levonorgestrel, with progesterone hormone receptor agonistic activity, used as a contraceptive and hormone replacement agent. Upon administration, desogestrel binds intracellular progesterone receptors in progesterone responsive tissue and the resultant complex interacts with DNA causing either gene transcription or gene repression. This eventually leads to an inhibition of gonadotropin releasing hormone (GnRH) secretion from the hypothalamus and a subsequent inhibition of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release. This prevents ovulation and alters the cervical mucus.NCI
code
  • C47476
sameAs
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