About: Dapiprazole Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Dapiprazole Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Dapiprazole Hydrochloride
UMLS_CUI
  • C0770916
CAS_Registry
  • 72822-13-0
FDA_UNII_Code
  • DS9UJN1I0X
Contributing_Source
  • FDA
Chemical_Formula
  • C19H27N5.HCl
Legacy_Concept_Name
  • Dapiprazole_Hydrochloride
FULL_SYN
  • Dapiprazole HydrochloridePTNCI
  • 1,2,4-Triazolo(4,3-a)pyridine, 5,6,7,8-tetrahydro-3-(2-(4-(2-methylphenyl)-1-piperazinyl)ethyl)-, monohydrochlorideSNNCI
  • DAPIPRAZOLE HYDROCHLORIDEPTFDADS9UJN1I0X
  • AF 2139CNNCI
  • Rev-EyesBRNCI
DEFINITION
  • An alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris. This prevents smooth muscle contraction and results in vasodilatation. Administered in the eye, dapiprazole hydrochloride produces miosis. In the heart, it may antagonize alpha-1 adrenoreceptors in myocytes causing a mild negative inotropic effect.NCI
code
  • C47469
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