About: Clocortolone Pivalate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Clocortolone Pivalate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Clocortolone Pivalate
UMLS_CUI
  • C0719380
CAS_Registry
  • 34097-16-0
FDA_UNII_Code
  • QBL8IZH14X
Contributing_Source
  • FDA
Chemical_Formula
  • C27H36ClFO5
Legacy_Concept_Name
  • Clocortolone_Pivalate
CHEBI_ID
  • CHEBI:59583
FULL_SYN
  • CLOCORTOLONE PIVALATEPTFDAQBL8IZH14X
  • 9-Chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalateSNNCI
  • ClodermBRNCI
  • Clocortolone PivalatePTNCI
DEFINITION
  • A glucocorticoid receptor agonist with metabolic, anti-inflammatory, and immunosuppressive activity. Clocortolone pivalate exerts its effect by interacting with specific intracellular receptors and subsequently binds to DNA to modify gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished.NCI
code
  • C47455
sameAs
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