About: Butoconazole Nitrate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Butoconazole Nitrate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Butoconazole Nitrate
UMLS_CUI
  • C0107509
CAS_Registry
  • 64872-77-1
FDA_UNII_Code
  • 4805237NP5
Contributing_Source
  • FDA
Chemical_Formula
  • C19H17Cl3N2S.HNO3
Legacy_Concept_Name
  • Butoconazole_Nitrate
CHEBI_ID
  • CHEBI:3241
FULL_SYN
  • BUTOCONAZOLE NITRATEPTFDA4805237NP5
  • FemstatSYNCI
  • ExelgynSYNCI
  • GynomykSYNCI
  • RS-35887CNNCI
  • (+-)-1-(4-(4-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-1H-imidazole MononitrateSNNCI
  • Butoconazole NitratePTNCI
  • Mycelex-3BRNCI
  • Gynazole-1BRNCI
DEFINITION
  • The nitrate salt form of butaconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane lipid composition. This alters cell permeability and leads to growth inhibition. Butaconazole nitrate is active against many dermatophytes and yeasts. It also contains antibacterial effects against some gram-positive organisms.NCI
code
  • C47427
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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