About: Butenafine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Butenafine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Butenafine Hydrochloride
UMLS_CUI
  • C0771847
CAS_Registry
  • 101827-46-7
FDA_UNII_Code
  • R8XA2029ZI
Contributing_Source
  • FDA
Chemical_Formula
  • C23H27N.HCl
Legacy_Concept_Name
  • Butenafine_Hydrochloride
CHEBI_ID
  • CHEBI:31325
FULL_SYN
  • N-((4-(1,1-Dimethylethyl)phenyl)methyl)-N-methyl-1-naphthalenemethanamine HydrochlorideSNNCI
  • Butenafine HydrochloridePTNCI
  • Lotrimin UltraBRNCI
  • BUTENAFINE HYDROCHLORIDEPTFDAR8XA2029ZI
  • KP-363CNNCI
  • MentaxBRNCI
  • N-4-tert-Butylbenzyl-N-methyl-1-naphthalenemethylamine HydrochlorideSNNCI
DEFINITION
  • The hydrochloride salt form of butenafine, a synthetic benzylamine derivative with fungicidal properties. Butenafine hydrochloride interferes with the biosynthesis of ergosterol, an important component of fungal cell membranes, by inhibiting the epoxidation of squalene. This alters fungal membrane permeability and causes growth inhibition. Butenafine hydrochloride is active against a number of dermatophytes, including Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum canis, Sporothrix schenckii, and yeasts, including Candida albicans and C. parapsilosis.NCI
code
  • C47426
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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