About: Atomoxetine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Atomoxetine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Atomoxetine Hydrochloride
UMLS_CUI
  • C1176420
CAS_Registry
  • 82248-59-7
FDA_UNII_Code
  • 57WVB6I2W0
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 475797
PDQ_Closed_Trial_Search_ID
  • 475797
Chemical_Formula
  • C17H21NO.ClH
Legacy_Concept_Name
  • Atomoxetine_Hydrochloride
CHEBI_ID
  • CHEBI:331697
FULL_SYN
  • TomoxetineSYNCI
  • (-)-N -Methyl-3-phenyl-3-(o-tolyloxy)-propylamine HydrochlorideSNNCI
  • Atomoxetine HydrochloridePTNCI
  • (-)-N-methyl-gamma(2-methylphenoxy)benzenepropamine HydrochlorideSNNCI
  • ATOMOXETINE HYDROCHLORIDEPTFDA57WVB6I2W0
  • StratteraBRNCI
DEFINITION
  • The hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Although its precise mechanism of action is unknown, atomoxetine appears to selectively inhibit the pre-synaptic norepinephrine transporter, resulting in inhibition of the presynaptic reabsorption of norepinephrine and prolongation of norepinephrine activity in the synaptic cleft. The effect on cognitive brain function may result in improved attention and decreased impulsivity and activity levels.NCI
code
  • C47405
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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