About: Apomorphine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Apomorphine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Apomorphine Hydrochloride
NSC_Code
  • 11442
UMLS_CUI
  • C0237406
CAS_Registry
  • 41372-20-7
FDA_UNII_Code
  • F39049Y068
Contributing_Source
  • FDA
Chemical_Formula
  • 2C17H17NO2.2ClH.H2O
Legacy_Concept_Name
  • Apomorphine_Hydrochloride
CHEBI_ID
  • CHEBI:31228
FULL_SYN
  • 4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-Tetrahydro-6-methyl-, Hydrochloride,(6aR)-SNNCI
  • Apomorphine HydrochloridePTNCI
  • N-Methylnorapomorphine HydrochlorideSYNCI
  • UprimaBRNCI
  • ApokynBRNCI
  • APOMORPHINE HYDROCHLORIDEPTFDAF39049Y068
  • 6ab-Aporphine-10,11-diol Hydrochloride HemihydrateSNNCI
DEFINITION
  • The hydrochloride salt form of apomorphine, a derivative of morphine and non-ergoline dopamine agonist with high selectivity for dopamine D2, D3, D4 and D5 receptors. Apomorphine hydrochloride acts by stimulating dopamine receptors in the nigrostriatal system, hypothalamus, limbic system, pituitary gland, and blood vessels. This enhances motor function, suppresses prolactin release, and causes vasodilation and behavioral effects. Apomorphine hydrochloride is used in the treatment of Parkinson's disease and erectile dysfunction. In addition, apomorphine hydrochloride acts on the chemoreceptor trigger zone and is used as a central emetic in the treatment of drug overdose.NCI
code
  • C47400
sameAs
is Has_Salt_Form of
is sameAs of
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