About: Pentetic Acid

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Pentetic Acid
rdfs:subClassOf	Metal Chelator
Has_Salt_Form	Pentetic Acid Calcium
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Pentetic Acid
NSC_Code	7340
UMLS_CUI	C0013254
CAS_Registry	67-43-6
FDA_UNII_Code	7A314HQM0I
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	42451
PDQ_Closed_Trial_Search_ID	42451
Chemical_Formula	C14H23N3O10
Legacy_Concept_Name	Pentetic_Acid
CHEBI_ID	CHEBI:35739
FULL_SYN	PENTETIC ACIDPTFDA7A314HQM0I Pentetic AcidPTNCI Diethylenetriamine Pentaacetic AcidSYNCI DetapacSYDTPNSC0007340 DTPAABNCI DetarexSYDTPNSC0007340 (Diethylenetriamine)pentaacetic acidSYDTPNSC0007340 DetapacBRNCI DetarexFBNCI Diethylenetriamine-N,N,N',N'',N''-pentaacetic AcidSNNCI
DEFINITION	An edetate and a chelating agent used in preparing radiopharmaceuticals. Pentetic acid (DTPA) has strong affinity for iron but also shows affinities for other heavy metals, thereby is used in the treatment of iron-storage disease and poisoning from heavy and radioactive metals. DTPA may chelate metallic moieties of unbound, extracellular radioimmunotherapeutics, thereby aggregating radioimmunotherapeutics locally to higher concentrations, and improving tumor cell radiocytotoxicity, while sparing normal tissues from the radiocytotoxic effects. In addition, DTPA is used in radioimaing procedures when complexes with radioisotopes, ex., Tc 99m or In 111.NCI
code	C460
sameAs	PENTETIC ACID PENTETIC ACID
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0006866
is someValuesFrom of	nodeID://b683183
is Has_Free_Acid_Or_Base_Form of	Pentetic Acid Calcium
is sameAs of	PENTETIC ACID PENTETIC ACID PENTETIC ACID PENTETIC ACID

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