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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Droperidol
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Droperidol
NSC_Code
  • 169874
UMLS_CUI
  • C0013136
CAS_Registry
  • 548-73-2
FDA_UNII_Code
  • O9U0F09D5X
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to prevent nausea and vomiting in patients who receive anesthesia before surgery. It is also used to treat anxiety. Droperidol is a type of antiemetic, adjunct anesthesia, and antipsychotic.NCI-GLOSS
  • A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 39227
PDQ_Closed_Trial_Search_ID
  • 39227
Chemical_Formula
  • C22H22FN3O2
Legacy_Concept_Name
  • Droperidol
CHEBI_ID
  • CHEBI:4717
FULL_SYN
  • droperidolPTNCI-GLOSSCDR0000467837
  • InapsineSYDTPNSC0169874
  • DROPERIDOLPTFDAO9U0F09D5X
  • InapsineBRNCI
  • DroperidolPTNCI
DEFINITION
  • A butyrophenone with anti-emetic, sedative and anti-anxiety properties. Although the exact mechanism through which droperidol exerts its effects is unknown, droperidol may block dopamine receptors in the chemoreceptor trigger zone (CTZ), which may lead to its anti-emetic effect. This agent may also bind to postsynaptic gamma-aminobutyric acid (GABA) receptors in the central nervous system (CNS), which increases the inhibitory effect of GABA and leads to sedative and anti-anxiety activities.NCI
code
  • C458
sameAs
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