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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • DNA Probes
rdfs:subClassOf
Semantic_Type
  • Nucleic Acid, Nucleoside, or Nucleotide
  • Indicator, Reagent, or Diagnostic Aid
Preferred_Name
  • DNA Probes
UMLS_CUI
  • C0012893
ALT_DEFINITION
  • Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.MSH2002_06_01
Legacy_Concept_Name
  • DNA_Probes
FULL_SYN
  • DNA ProbesPTNCI
DEFINITION
  • A piece of DNA that has been labeled, usually radioactively or with a fluorescent dye, which is used in hybridization studies. Applications include Northern and Southern blots, in situ hybridization techniques, and diagnostic tests. DNA probes can be highly specific or degenerate.NCI
code
  • C451
sameAs
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