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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Disulfiram
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Disulfiram
NSC_Code
  • 25953
UMLS_CUI
  • C0012772
CAS_Registry
  • 97-77-8
FDA_UNII_Code
  • TR3MLJ1UAI
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that slows the metabolism of retinoids, allowing them to act over a longer period of time.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42291
PDQ_Closed_Trial_Search_ID
  • 42291
Chemical_Formula
  • C10H20N2S4
Legacy_Concept_Name
  • Disulfiram
CHEBI_ID
  • CHEBI:4659
FULL_SYN
  • disulfiramPTNCI-GLOSSCDR0000045444
  • Tetraethylthioperoxydicarbonic DiamidePTDCP00813
  • DSABNCI
  • Bis(diethylthiocarbamoyl) DisulfideSNNCI
  • TTDABNCI
  • Tetraethylthiuram DisulfideSNNCI
  • AntabuseSYDTPNSC0025953
  • Tetraethylthioperoxydicarbonic DiamideSNNCI
  • DISULFIRAMPTFDATR3MLJ1UAI
  • AntabuseBRNCI
  • DisulfiramSYDTPNSC0025953
  • TeturaminSYNCI
  • DisulfiramPTNCI
DEFINITION
  • A carbamoyl derivate used in the treatment of alcoholism. Disulfiram irreversibly inhibits acetaldehyde dehydrogenase that oxidizes the ethanol metabolite acetaldehyde into acetic acid. This leads to an accumulation of acetaldehyde that produces a variety of very unpleasant symptoms referred to as the disulfiram-alcohol reaction. This reaction includes , but is not limited to, flushing, headache, respiratory difficulty, nausea,vomiting, sweating, thirst, chest pain, tachycardia, blurred vision and hypotension.NCI
code
  • C447
sameAs
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