About: Distamycin Antineoplastic Antibiotic     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Distamycin Antineoplastic Antibiotic
rdfs:subClassOf
Semantic_Type
  • Chemical Viewed Functionally
Preferred_Name
  • Distamycin Antineoplastic Antibiotic
UMLS_CUI
  • C0012750
Legacy_Concept_Name
  • Distamycin_Antibiotic
FULL_SYN
  • DistamycinsSYNCI
  • Distamycin Antineoplastic AntibioticPTNCI
DEFINITION
  • An antineoplastic antibiotic isolated from the bacterium Streptomyces distallicus. Distamycin antibiotics bind to the minor groove of DNA, preferentially to adenine-thymine (A-T) rich sequences, thereby inhibiting DNA replication and RNA transcription. In addition to their antitumor effects, these agents possess antiviral and antiprotozoal activities.NCI
code
  • C446
sameAs
http://linked.open...y/mesh/hasConcept
is rdfs:subClassOf of
is sameAs of
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