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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ditiocarb
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Ditiocarb
UMLS_CUI
  • C0012194
CAS_Registry
  • 147-84-2
FDA_UNII_Code
  • 99Z2744345
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 40247
PDQ_Closed_Trial_Search_ID
  • 40247
Chemical_Formula
  • C5H11NS2
Legacy_Concept_Name
  • Diethyldithiocarbamate
FULL_SYN
  • DiethyldithiocarbamateSYNCI
  • DiethyldioneSYNCI
  • DTCABNCI
  • DiethyldithioneSYNCI
  • Diethyldithiocarbamic AcidSYNCI
  • DDTCABNCI
  • DIECAABNCI
  • Diethylcarbamodithioic AcidSYNCI
  • Diethylcarbamodithioic AcidPTDCP01360
  • DITIOCARBPTFDA99Z2744345
  • Diethyldithiocarbaminic AcidSYNCI
  • DitiocarbPTNCI
DEFINITION
  • A sulfhydryl-containing carbamate that is the primary in vivo metabolite of disulfiram. Diethyldithiocarbamate chelates zinc, thereby inhibiting metalloproteinases, thereby preventing the degradation of the extracellular matrix and inhibiting an initial step in cancer metastasis and angiogenesis. A known inhibitor of superoxide dismutase, this agent can either potentiate or protect against cell oxidative damage caused by ionizing radiation, depending on the time of administration. (NCI04)NCI
code
  • C432
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