About: Well Differentiated Liposarcoma     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Well Differentiated Liposarcoma
equivalentClass
Semantic_Type
  • Neoplastic Process
Preferred_Name
  • Well Differentiated Liposarcoma
UMLS_CUI
  • C1370889
ALT_DEFINITION
  • An intermediate malignant mesenchymal neoplasm composed entirely or in part of mature adipocytes that vary in cell size and show at least focal nuclear atypia in adipocytes and stromal cells. Recurrent cytogenetic aberrations are specifically associated with this entity: supernumerary ring and giant marker chromosomes with amplification of MDM2 and, often, CDK4.NCI
ICD-O-3_Code
  • 8851/3
Neoplastic_Status
  • Malignant
Legacy_Concept_Name
  • Well-Differentiated_Liposarcoma
FULL_SYN
  • Well Differentiated LiposarcomaPTNCI
  • Well Differentiated LiposarcomaSYNCITCGA
DEFINITION
  • A locally aggressive malignant neoplasm composed of mature adipocytes showing cell size variation and nuclear atypia. It is often associated with the presence of hyperchromatic multinucleated stromal cells, and varying numbers of lipoblasts. There are three histologic subtypes, sclerosing, inflammatory, and spindle cell liposarcoma. These tumors do not usually metastasize unless they undergo dedifferentiation.NCI
code
  • C4250
is rdf:first of
is someValuesFrom of
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