About: Diltiazem Hydrochloride

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Diltiazem Hydrochloride
rdfs:subClassOf	CALCIUM CHANNEL BLOCKERS nodeID://b666894
Has_Free_Acid_Or_Base_Form	DILTIAZEM
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Diltiazem Hydrochloride
UMLS_CUI	C0700940
CAS_Registry	33286-22-5
FDA_UNII_Code	OLH94387TE
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	40122
PDQ_Closed_Trial_Search_ID	40122
Chemical_Formula	C22H26N2O4S.HCl
Legacy_Concept_Name	Diltiazem_Hydrochloride
CHEBI_ID	CHEBI:645509
FULL_SYN	Diltiazem HydrochloridePTNCI Diltiazem HClSYNCI DILTIAZEM HYDROCHLORIDEPTFDAOLH94387TE CardizemBRNCI Diltiazem HydrochloridePTDCP32070
DEFINITION	A benzothiazepine calcium channel blocking agent. Diltiazem hydrochloride inhibits the transmembrane influx of extracellular calcium ions into select myocardial and vascular smooth muscle cells, causing dilatation of coronary and systemic arteries and decreasing myocardial contractility. Because of its vasodilatory activity, this agent has been shown to improve the microcirculation in some tumors, thereby potentially improving the delivery of antineoplastic agents to tumor cells. (NCI04)NCI
code	C398
sameAs	Diltiazem Hydrochloride
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0353526
is Has_Salt_Form of	DILTIAZEM
is sameAs of	Diltiazem Hydrochloride

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