About: Thyroid Gland Medullary Carcinoma

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Attributes	Values
rdf:type	Class
rdfs:label	Thyroid Gland Medullary Carcinoma
equivalentClass	nodeID://b635462
Concept_In_Subset	NCI CTEP Simplified Disease Classification Terminology NCI CTEP SDC Thyroid Cancer Sub-Category Terminology Clinical Data Interchange Standards Consortium Terminology CDISC SDTM Terminology CDISC SEND Terminology CDISC SEND Tumor Findings Results Terminology
Semantic_Type	Neoplastic Process
Preferred_Name	Thyroid Gland Medullary Carcinoma
UMLS_CUI	C0238462
Contributing_Source	CDISC CTEP
ALT_DEFINITION	Cancer that develops in C cells of the thyroid. The C cells make a hormone (calcitonin) that helps maintain a healthy level of calcium in the blood.NCI-GLOSS A neuroendocrine malignant epithelial neoplasm arising from C-cells of the thyroid gland.CDISC
Neoplastic_Status	Malignant
Legacy_Concept_Name	Medullary_Thyroid_Carcinoma
FULL_SYN	Thyroid Gland Medullary CarcinomaPTNCI Medullary Thyroid Gland CarcinomaSYNCI Medullary thyroid carcinomaPTCTEP10027105 MEDULLARY THYROID GLAND CARCINOMASYCDISC medullary thyroid cancerPTNCI-GLOSSCDR0000044550 Medullary Carcinoma of the ThyroidSYNCI MEDULLARY CARCINOMA OF THE THYROIDSYCDISC Thyroid Gland Medullary CarcinomaSYNCITCGA Medullary Thyroid CancerSYNCI MEDULLARY THYROID CANCERSYCDISC MTCABNCI Medullary Carcinoma of Thyroid GlandSYNCI MEDULLARY CARCINOMA OF THYROID GLANDSYCDISC C Cell CarcinomaSYNCI Thyroid Medullary CarcinomaSYNCI Medullary Thyroid CarcinomaSYNCI MTCSYCDISC MEDULLARY THYROID CARCINOMASYCDISC THYROID MEDULLARY CARCINOMASYCDISC C CELL CARCINOMASYCDISC THYROID GLAND NEUROENDOCRINE CARCINOMASYCDISC Thyroid Gland Neuroendocrine CarcinomaSYNCI CARCINOMA, C-CELL, MALIGNANTPTCDISC Parafollicular Cell CarcinomaSYNCI PARAFOLLICULAR CELL CARCINOMASYCDISC MEDULLARY CARCINOMA OF THE THYROID GLANDSYCDISC Medullary CarcinomaSYNCI Medullary Carcinoma of the Thyroid GlandSYNCI Medullary Carcinoma of ThyroidSYNCI MEDULLARY CARCINOMA OF THYROIDSYCDISC MEDULLARY CARCINOMASYCDISC
DEFINITION	A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. It is closely associated with multiple endocrine neoplasia syndromes. Approximately 10% to 20% of medullary thyroid carcinomas are familial. Patients usually present with a thyroid nodule that is painless and firm. In the majority of cases nodal involvement is present at diagnosis. Surgery is the preferred treatment for both primary lesions and recurrences. This carcinoma is generally not very sensitive to radiation and almost unresponsive to chemotherapy.NCI
code	C3879
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