About: Transgenic Lymphocyte Immunization Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Transgenic Lymphocyte Immunization Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Transgenic Lymphocyte Immunization Vaccine
UMLS_CUI
  • C1327996
In_Clinical_Trial_For
  • Prostate cancer
PDQ_Open_Trial_Search_ID
  • 315736
PDQ_Closed_Trial_Search_ID
  • 315736
Legacy_Concept_Name
  • Transgenic_Lymphocyte_Immunization_Vaccine
FULL_SYN
  • Transgenic Lymphocyte Immunization VaccinePTNCI
  • TLI VaccineSYNCI
DEFINITION
  • A vaccine consisting of a preparation of allogeneic lymphocytes that encode a gene for telomerase. In transgenic lymphocyte immunization, the transgenic cells are infused into the patient, where they serve as antigen- presenting cells (APCs) with the dual function of antigen synthesis and presentation. Vaccination produces an immune response targeting cancer cells expressing telomerase. (NCI04)NCI
code
  • C38720
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