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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • CC-8490
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • CC-8490
UMLS_CUI
  • C1328106
In_Clinical_Trial_For
  • High-grade gliomas
ALT_DEFINITION
  • A substance that is being studied in the treatment of brain cancer. It belongs to the family of drugs called benzopyrans.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 346082
PDQ_Closed_Trial_Search_ID
  • 346082
Legacy_Concept_Name
  • CC-8490
FULL_SYN
  • CC-8490PTNCI-GLOSSCDR0000350227
  • CC-8490CNNCI
  • CC-8490PTNCI
  • SPC8490CNNCI
DEFINITION
  • A benzopyran with potential antineoplastic activity. CC-8490 acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms. (NCI04)NCI
code
  • C38711
http://linked.open...y/mesh/hasConcept
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