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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Rectal Route of Administration
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Functional Concept
Preferred_Name
  • Rectal Route of Administration
UMLS_CUI
  • C1527425
FDA_Table
  • Route of Administration (C-DRG-00301)
Contributing_Source
  • CDISC
  • FDA
ALT_DEFINITION
  • Administration to the rectum. (FDA)CDISC
Legacy_Concept_Name
  • Rectal_Route_of_Drug_Administration
FULL_SYN
  • RECTALABFDA016
  • RECTALPTFDA016
  • RECTALPTFDA
  • RectalSYNCI
  • RECTALPTCDISC
  • Rectal Route of AdministrationPTNCI
  • Per RectumSYNCI
DEFINITION
  • The introduction of a substance into the gastrointestinal tract by the way of the rectum, usually for systemic action. Depending on the molecular structure, drugs cross the rectal wall via either intercellular or tight junctions interconnecting the mucosal cells. Drug absorption is usually around 50% of normal oral dose. Due to the drainage pattern of the rectal veins, the hepatic first-pass effect tends to increase as the dosage form is placed deeper into the rectum. Solid suppositories represent greater than 98% of all rectal dosage forms.NCI
code
  • C38295
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