About: 6-Aminonicotinamide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • 6-Aminonicotinamide
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • 6-Aminonicotinamide
NSC_Code
  • 21206
UMLS_CUI
  • C0000610
Legacy_Concept_Name
  • _6-Aminonicotinamide
FULL_SYN
  • 6-ANABNCI
  • U-8774CNNCI
  • AminonicotinamideSYNCI
  • 6-AminonicotinamidePTNCI
DEFINITION
  • A synthetic analogue and nicotinamide antagonist with cytotoxic properties, 6-Aminonicotinamide forms an abnormal NAD (ubiquitous metabolic pathway coenzyme) analog that inhibits NAD-dependent enzyme activity associated with ATP production. 6-Aminonicotinamide impairs cartilage formation, may have teratogenic effects, and enhances the effect of radiation and cisplatin treatment (formation of platinum-DNA complexes). (NCI04)NCI
code
  • C38127
sameAs
http://linked.open...y/mesh/hasConcept
is sameAs of
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