About: Autologous Heat-Shock Protein 70 Peptide Vaccine AG-858     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Autologous Heat-Shock Protein 70 Peptide Vaccine AG-858
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Autologous Heat-Shock Protein 70 Peptide Vaccine AG-858
UMLS_CUI
  • C1328058
In_Clinical_Trial_For
  • Chronic myelogenous leukemia; high risk breast cancer
PDQ_Open_Trial_Search_ID
  • 334949
PDQ_Closed_Trial_Search_ID
  • 334949
Legacy_Concept_Name
  • Autologous_Heat-Shock_Protein_70_Peptide_Vaccine
FULL_SYN
  • Autologous Heat-Shock Protein 70 Peptide Vaccine AG-858PTNCI
  • AG-858CNNCI
DEFINITION
  • A recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. HSP70 associates with antigenic peptides, transporting them into antigen presenting cells (APC) for processing. Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models. (NCI04)NCI
code
  • C37448
is someValuesFrom of
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