About: Chloramphenicol     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Chloramphenicol
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Chloramphenicol
NSC_Code
  • 3069
UMLS_CUI
  • C0008168
CAS_Registry
  • 56-75-7
FDA_UNII_Code
  • 66974FR9Q1
Contributing_Source
  • FDA
Chemical_Formula
  • C11H12Cl2N2O5
Legacy_Concept_Name
  • Chloramphenicol
CHEBI_ID
  • CHEBI:17698
FULL_SYN
  • [R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamideSNNCI
  • CHLORAMPHENICOLPTFDA66974FR9Q1
  • ChloramphenicolPTNCI
  • ChloramphenicolSYDTPNSC0003069
  • ChloramphenicolPTDCP00420
DEFINITION
  • A semisynthetic, broad-spectrum antibiotic derived from Streptomyces venequelae with primarily bacteriostatic activity. Chloramphenicol diffuses through the bacterial cell wall and reversibly binds to the bacterial 50S ribosomal subunit. The binding interferes with peptidyl transferase activity, thereby prevents transfer of amino acids to the growing peptide chains and blocks peptide bond formation. As a result bacterial protein synthesis is blocked and impede bacterial cell proliferation.NCI
code
  • C363
sameAs
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