About: Sinus Histiocytosis with Massive Lymphadenopathy     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Sinus Histiocytosis with Massive Lymphadenopathy
equivalentClass
Semantic_Type
  • Disease or Syndrome
Preferred_Name
  • Sinus Histiocytosis with Massive Lymphadenopathy
UMLS_CUI
  • C0019625
Legacy_Concept_Name
  • Rosai-Dorfman_Disease
FULL_SYN
  • Sinus Histiocytosis with Massive LymphadenopathyPTNCI
  • Rosai-Dorfman DiseaseSYNCI
DEFINITION
  • A rare non-neoplastic disorder of unknown etiology characterized by distention of the lymph node sinuses and sinusoidal histiocytic infiltration. The histiocytes characteristically contain ingested lymphocytes. It is usually manifested with cervical lymphadenopathy, fever, leukocytosis, and hypergammaglobulinemia. . It can affect extranodal sites, including the skin, bones, and the respiratory tract. It usually regresses spontaneously.NCI
code
  • C36075
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