About: N-cym Protein     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • N-cym Protein
equivalentClass
OMIM_Number
  • 605374
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • N-cym Protein
UMLS_CUI
  • C1333228
Legacy_Concept_Name
  • DNA-Binding_Transcriptional_Activator-NCYM
FULL_SYN
  • NCYM ProteinSYNCI
  • N-cym ProteinPTNCI
  • NCYMSYNCI
  • DNA-Binding Transcriptional ActivatorSYNCI
  • MYCNOSSYNCI
  • N-myc Opposite StrandSYNCI
  • DNA-Binding Transcriptional Activator NCYMSYNCI
Swiss_Prot
  • P40205
DEFINITION
  • N-cym protein (109 aa, ~12 kDa) is encoded by the human MYCNOS gene. This protein may play a role in embryonic development.NCI
DesignNote
  • Expressed in fetal brain, lung, liver, and kidney by human NCYM Gene, 109-aa 12-kDa DNA-Binding Transcriptional Activator NCYM contains a helix-loop-helix motif and a basic region. NCYM may function as a DNA-binding protein during normal fetal development and is implicated in the pathogenesis of human tumors. The NCYM transcription unit is located on the opposite strand to NMYC, with extensive overlap between the 5-prime ends of the two units. NMYC and NCYM appear to be coregulated under basal growth conditions and in response to retinoic acid.
code
  • C33964
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