About: Hepatocellular Carcinoma

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About: Hepatocellular Carcinoma Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Hepatocellular Carcinoma
equivalentClass	nodeID://b633554
Concept_In_Subset	NCI CTEP Simplified Disease Classification Terminology NCI CTEP SDC Liver and Hepatobiliary Cancer Sub-Category Terminology Clinical Data Interchange Standards Consortium Terminology CDISC SDTM Terminology CDISC SEND Terminology CDISC SEND Tumor Findings Results Terminology
Semantic_Type	Neoplastic Process
Preferred_Name	Hepatocellular Carcinoma
UMLS_CUI	C0019204
Contributing_Source	CDISC CTEP
ALT_DEFINITION	A type of adenocarcinoma and the most common type of liver tumor.NCI-GLOSS A malignant neoplasm arising from hepatocytes.CDISC
ICD-O-3_Code	8170/3
Neoplastic_Status	Malignant
Legacy_Concept_Name	Hepatocellular_Carcinoma
FULL_SYN	PRIMARY CARCINOMA OF LIVER CELLSSYCDISC hepatocellular carcinomaPTNCI-GLOSSCDR0000046363 Liver Cell Cancer (Hepatocellular Carcinoma)SYNCI Carcinoma of Liver CellsSYNCI Hepatocellular CarcinomaPTNCI CARCINOMA OF LIVER CELLSSYCDISC HCCABNCI Primary Carcinoma of the Liver CellsSYNCI PRIMARY CARCINOMA OF THE LIVER CELLSSYCDISC CARCINOMA, HEPATOCELLULAR, MALIGNANTPTCDISC HCCSYCDISC Carcinoma of the Liver CellsSYNCI CARCINOMA OF THE LIVER CELLSSYCDISC Hepatocellular carcinomaPTCTEP10049010 hepatomaPTNCI-GLOSSCDR0000046661 HepatomaSYNCI Liver Cell CarcinomaSYNCI LIVER CELL CARCINOMASYCDISC HEPATOMASYCDISC Hepatocellular CarcinomaSYNCITCGA Primary Carcinoma of Liver CellsSYNCI
DEFINITION	A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation.NCI
code	C3099
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is rdfs:subClassOf of	Hepatocellular Carcinoma by AJCC v6 Stage Hepatocellular Carcinoma by AJCC v7 Stage
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