About: Angiofollicular Lymphoid Hyperplasia     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Angiofollicular Lymphoid Hyperplasia
equivalentClass
Semantic_Type
  • Disease or Syndrome
Preferred_Name
  • Angiofollicular Lymphoid Hyperplasia
UMLS_CUI
  • C0017531
ALT_DEFINITION
  • A rare disorder in which growths that are benign (not cancer) develop in lymph node tissue.NCI-GLOSS
Legacy_Concept_Name
  • Angiofollicular_Lymphoid_Hyperplasia
FULL_SYN
  • Castleman's diseasePTNCI-GLOSSCDR0000046043
  • Angiofollicular Lymphoid HyperplasiaPTNCI
  • AFLHABNCI
  • GLNHABNCI
  • Castleman's TumorSYNCI
  • Castleman DiseaseSYNCI
  • Giant Lymph Node HyperplasiaSYNCI
  • Castleman's DiseaseSYNCI
DEFINITION
  • A disorder characterized by lymphoid hyperplasia in the lymph nodes. There are two histologic variants recognized: the hyaline-vascular type and the plasma cell type. In the hyaline vascular type there are hyalinized vessels present in the lymphoid follicles. In the plasma cell type there is pronounced plasma cell proliferation. Clinically, the disease may be localized; manifested with localized lymphadenopathy, or multicentric; manifested with generalized lymphadenopathy, fever, organomegaly, and sometimes POEMS syndrome. In contrast to patients with localized disease who are usually cured following resection of the lesion, patients with the multicentric form of the disease may follow a progressive clinical course, complicated by infection, Kaposi sarcoma or lymphoma.NCI
code
  • C3056
http://linked.open...y/mesh/hasConcept
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