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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Lerisetron
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Lerisetron
UMLS_CUI
  • C0758799
CAS_Registry
  • 143257-98-1
FDA_UNII_Code
  • Q36R82SXRG
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance being studied in the treatment of nausea and vomiting caused by cancer treatment. Lerisetron is a type of serotonin receptor antagonist and a type of antiemetic.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 37821
PDQ_Closed_Trial_Search_ID
  • 37821
Chemical_Formula
  • C18H20N4
Legacy_Concept_Name
  • Lerisetron
FULL_SYN
  • lerisetronPTNCI-GLOSSCDR0000044876
  • LERISETRONPTFDAQ36R82SXRG
  • F-0930-RS2CNNCI
  • 1-Phenyl-Methyl-2-Piperazinyl-1H-Benzimidazole HydrochlorideSNNCI
  • LerisetronPTNCI
DEFINITION
  • The hydrochloride salt of a 2-piperazinylbenzimidazole-derivative serotonin type 3 (5-HT3) receptor antagonist with antiemetic activity. Lerisetron specifically binds to 5-HT3 receptors, located peripherally on vagus nerve terminals and centrally in the chemoreceptor trigger zone (CTZ) of the area postrema, which may result in suppression of chemotherapy-induced nausea and vomiting.NCI
code
  • C30143
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