About: ALVAC-CEA (6D)-B7.1 Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • ALVAC-CEA (6D)-B7.1 Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • ALVAC-CEA (6D)-B7.1 Vaccine
NSC_Code
  • 715616
UMLS_CUI
  • C1515849
Legacy_Concept_Name
  • ALVAC-CEA_6D_B7_1_Vaccine
FULL_SYN
  • ALVAC-CEA (6D)-B7.1 VaccinePTNCI
  • ALVAC-CEA (6D)-B7.1SYNCI
DEFINITION
  • A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived from the canarypox virus. ALVAC-CEA (6D)-B7.1 vaccine expresses both a highly immunogenic analogue (6D) of the immunodominant epitope of carcinoembryonic antigen (CEA) and B7.1 (also known as CD80), the natural ligand for the T-cell antigen CD28. This agent was designed to stimulate host immune responses against tumor cells that express CEA. (NCI04)NCI
code
  • C29982
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